Michael Karin, Ph.D.

University of California, San Diego
email: none

Grants

Role of IKKa in Mammary Gland Development 2001 (Cycle VII)
RFA (Request for Applications) 7PB-0071 $563,696
Regaining Control over Breast Cancer Cells 1995 (Cycle I)
Research Project Awards 1RB-0214 $270,132


NF-kappaB in cancer: from innocent bystander to major culprit.
  Periodical: Nature Reviews. Cancer
  Author(s): Karin M, Cao Y, Greten FR, Li ZW
  Yr: 2002 Vol: 2 Nbr: 4 Pgs: 301-310
  Associated Grant: Role of IKKa in Mammary Gland Development
 
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain.
  Periodical: Genes and Development
  Author(s): Baud V, Liu ZG, Bennett B, Suzuki N, Xia Y, Karin M.
  Yr: 1999 Vol: 13 Nbr: 10 Pgs: 1297-1308
  Associated Grant: Regaining Control over Breast Cancer Cells
 
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
  Periodical: Nature
  Author(s): Rothwarf DM, Zandi E, Natoli G, and Karin M
  Yr: 1998 Vol: 395 Nbr: 6699 Pgs: 297-300
  Associated Grant: Regaining Control over Breast Cancer Cells
 
Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
  Periodical: Proceedings of the National Academy of Sciences of the United States of America
  Author(s): Li N, and Karin M
  Yr: 1998 Vol: 95 Nbr: 22 Pgs: 13012-13017
  Associated Grant: Regaining Control over Breast Cancer Cells
 
Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate
  Periodical: Science
  Author(s): Zandi E, Chen Y, and Karin M
  Yr: 1998 Vol: 281 Nbr: 5381 Pgs: 1360-3
  Associated Grant: Regaining Control over Breast Cancer Cells
 
AP-1 function and regulation
  Periodical: Current Opinions in Cell Biology
  Author(s): Karin M, Liu Z-G, and Zandi E
  Yr: 1997 Vol: 9 Nbr: 2 Pgs: 240-246
  Associated Grant: Regaining Control over Breast Cancer Cells
 
Molecular cloning and characterization of human JNKK2, a novel June NH2-terminal kinase-specific kinase
  Periodical: Molecular Biology of the Cell
  Author(s): Wu Z, Wu J, Jacinto E. and Karin M
  Yr: 1997 Vol: 17 Nbr: 12 Pgs: 7407-16
  Associated Grant: Regaining Control over Breast Cancer Cells
 
Three distinct signalling responses by murine fibroblasts to genotoxic stress
  Periodical: Nature
  Author(s): Liu ZG, Baskaran R, Lea-Chou ET, Wood LD, Chen Y, Karin M, and Wang JY
  Yr: 1996 Vol: 384 Nbr: 6606 Pgs: 273-276
  Associated Grant: Regaining Control over Breast Cancer Cells
 
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
  Periodical: Cell
  Author(s): Liu Z-G, Hsu H, Goeddel DV, and Karin M
  Yr: 1996 Vol: 87 Nbr: 3 Pgs: 565-576
  Associated Grant: Regaining Control over Breast Cancer Cells