Juan Zapata, Ph.D.

The Burnham Institute for Medical Research
email: none

Grants

TRAF-regulated Signal Transduction in Breast Cancer 1997 (Cycle III)
Postdoctoral Fellowship 3FB-0093 $75,600


Prognostic significance of apoptosis regulators in breast cancer
  Periodical: Endocrine-Related Cancer
  Author(s): Krajewski, S., Krajewska, M., Turner, B.C., Pratt, H., Howard, B., Zapata, J.M., et al.
  Yr: 1999 Vol: 6 Nbr: 1 Pgs: 29-40
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers
  Periodical: Cancer Research
  Author(s): Gil, J., Yamamoto, H., Zapata, J.M., Reed, J.C. and Perucho M.
  Yr: 1999 Vol: 59 Nbr: 9 Pgs: 2034-2037
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation
  Periodical: Journal of Biological Chemistry
  Author(s): Leo E, Welsch K, Matsuzawa S, Zapata JM, Mitchell RS, Ely KR, and Reed JC
  Yr: 1999 Vol: 274 Nbr: 32 Pgs: 22414-22412
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Missense mutations at threonine 169 of Bax, a hot spot in gastrointestinal cancer, inhibit its apoptotic activity.
  Periodical: Cancer Research
  Author(s): Gil J, Yamamoto H, Zapata JM, Reed JC, and Perucho M.
  Yr: 1999 Vol: 59 Nbr: Pgs: 2034-2037
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Espression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors
  Periodical: Breast Cancer Research and Treatment
  Author(s): Zapata JM, Krajewska M, Krajewski S, Huang R-P, Takayama S, and Adamson E, et al
  Yr: 1998 Vol: 47 Nbr: Pgs: 129-140
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
p53-inducible human homologue of drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1
  Periodical: Embo Journal
  Author(s): Matsuzawa S, Takayama S, Froesch B, Zapata JM, and Reed JC
  Yr: 1998 Vol: 17 Nbr: 10 Pgs: 2736-2747
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and turmor tissues
  Periodical: American Journal of Pathology
  Author(s): Krajewska M, Krajewski S, Zapata JM, Van Arsdale T, Gascoyne RD, Berern K, McFadden, et al
  Yr: 1998 Vol: 152 Nbr: 6 Pgs: 1549-61
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normaltissues and tumor cell lines
  Periodical: Cancer Research
  Author(s): Takayama S, Krajewski S, Krajewska M, Kitada S, aand Zapata JM, et al
  Yr: 1998 Vol: 58 Nbr: 14 Pgs: 3116-3131
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Granzyme release and caspase activation in activated human T-Lymphocytes
  Periodical: Journal of Biological Chemistry
  Author(s): Zapata JM, Takahashi R, Salvesen GS, and Reed JC
  Yr: 1998 Vol: 273 Nbr: 12 Pgs: 6916-6920
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer
 
Immunohistochmical analysis of in vivo patterns ofTRAF-3 expression, a member of the TNF receptor-associated factor family
  Periodical: Journal of Immunology
  Author(s): Krajewski S, Zapata JM, Krajewska M, VanArsdale T,Shabaik A, Gascoyne RD, and Reed JC
  Yr: 1997 Vol: 159 Nbr: Pgs: 5841-5852
  Associated Grant: TRAF-regulated Signal Transduction in Breast Cancer