Kathryn DeFea, Ph.D.

University of California, Riverside
email: katied@citrus.ucr.edu

Grants

Trypsin-like Proteases as Metastatic Agents in Breast Cancer 2001 (Cycle VII)
New Investigator 7KB-0093 $295,893


Constitutive protease-activated-receptor-2 mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and 2.
  Periodical: Journal of Biological Chemistry
  Author(s): Ge L, Shenoy SK, Lefkowitz RJ, Defea KA.
  Yr: 2004 Vol: Nbr: Pgs:
  Associated Grant: Trypsin-like Proteases as Metastatic Agents in Breast Cancer
 
A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis.
  Periodical: Journal of Biological Chemistry
  Author(s): Ge L, Ly Y, Hollenberg MD, DeFea K.
  Yr: 2003 Vol: 278 Nbr: 36 Pgs: 34418-26
  Associated Grant: Trypsin-like Proteases as Metastatic Agents in Breast Cancer
 
Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins.
  Periodical: Circulation Research
  Author(s): Lin T, Zeng L, Liu Y, DeFea K, Schwartz MA, Chien S, Shyy JY.
  Yr: 2003 Vol: 92 Nbr: 12 Pgs: 1296-304
  Associated Grant: Trypsin-like Proteases as Metastatic Agents in Breast Cancer