Jeffrey Smith, Ph.D.

The Burnham Institute for Medical Research
email: none

Grants

Maspin: Breast Cancer Suppression through Enzyme Inhibition? 2004 (Cycle 10)
STEP Award 10WB-0083 $196,115
Protease Fingerprinting to Diagnose Breast Cancer 1999 (Cycle V)
IDEAS II 5JB-0033 $285,405
Targeting T Cells to Breast Cancer 1997 (Cycle III)
ITaMoCAs 3CB-0249 $388,050
Prevention of Breast Cancer by Blocking Integrin Function 1995 (Cycle I)
Research Project Awards 1RB-0020 $545,057


Maspin alters the carcinoma proteome.
  Periodical: FASEB Journal
  Author(s): Chen EI, Florens L, Axelrod FT, Monosov E, Barbas CF 3rd, Yates JR 3rd, Felding-Habermann
  Yr: 2005 Vol: 19 Nbr: Pgs: 1123-4
  Associated Grant: Maspin: Breast Cancer Suppression through Enzyme Inhibition?
 
A unique substrate recognition profile for matrix metalloproteinase-2.
  Periodical: Journal of Biological Chemistry
  Author(s): Chen EI, Kridel SJ, Howard EW, Li W, Godzik A, Smith JW.
  Yr: 2002 Vol: 277 Nbr: 6 Pgs: 4485-91
  Associated Grant: Protease Fingerprinting to Diagnose Breast Cancer
 
Substrate hydrolysis by matrix metalloproteinase-9
  Periodical: Journal of Biological Chemistry
  Author(s): Kridel SJ, Chen E, Kotra LP, Howard EW, Mobashery S, and Smith JW
  Yr: 2001 Vol: 276 Nbr: 23 Pgs: 20572-20578
  Associated Grant: Protease Fingerprinting to Diagnose Breast Cancer
 
A substrate phage enzyme-linked immunoabsorbant assay to profile panels of proteases
  Periodical: Analytical Biochemistry
  Author(s): Kridel SJ, Chen E, and Smith JW
  Yr: 2001 Vol: 294 Nbr: 2 Pgs: 176-184
  Associated Grant: Protease Fingerprinting to Diagnose Breast Cancer
 
A series of function blocking antibodies against the alpha-v beta3 integrin bind allosteric to theligand binding site and induce ligand dissociation
  Periodical: Cell Communication and Adhesion
  Author(s): Lin ECK, Carron CP, Meyer DM, and Smith JW
  Yr: 1998 Vol: 6 Nbr: 6 Pgs: 451-464
  Associated Grant: Prevention of Breast Cancer by Blocking Integrin Function
 
Alpha-v integrins mediate adhesion and migration of breast carcinoma cell lines
  Periodical: Clinical & Experimental Metastasis
  Author(s): Wong NC, Mueller BM, Barbas CF, Ruminski P, Quarata V, Lin ECK, and Smith JW
  Yr: 1998 Vol: 16 Nbr: 1 Pgs: 50-61
  Associated Grant: Prevention of Breast Cancer by Blocking Integrin Function