Alex Strongin, Ph.D.

The Burnham Institute for Medical Research
email: strongin@burnham.org

Grants

Spatial Control of Matrix Proteolysis in Breast Cancer 1999 (Cycle V)
IDEAS II 5JB-0094 $0
Spatial Control of Matrix Proteolysis in Breast Cancer 1999 (Cycle V)
IDEAS II 5JB-0094A $340,383
How are Collagenses Involved in Breast Cancer Metastasis? 1996 (Cycle II)
Research Project Awards 2RB-0028 $584,513


MT1-MMP Initiates Activation of pro-MMP-2 and Integrin avb3 Promotes Maturation of MMP-2 in Breast Carcinoma Cells
  Periodical: Experimental Cell Research
  Author(s): Dreyugina EI, Ratnikov B, Monosov E, Postnova TI, DiScipio R, Smith JW, and Strongin AY
  Yr: 2001 Vol: 263 Nbr: Pgs: 209-223
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Characterization of Matrix Metalloproteinase-26, a Novel Metalloproteinase Widely Expressed in Cancer Cells of Epithelial Origin
  Periodical: Biochemical Journal
  Author(s): Marchenko GN, Ratnikov BI, Rozanov DV, Godzik A, Deryugina EI, and Strongin AY
  Yr: 2001 Vol: 356 Nbr: Pgs: 705-718
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
MMP-28, a new Human Matrix Metalloproteinase with an Unusual Cysteine-switch Sequence in Widely Expressed in Tumors
  Periodical: Gene
  Author(s): Marchenko GN and Strongin AY
  Yr: 2001 Vol: 265 Nbr: Pgs: 87-93
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Matrix-dependent Proteolysis of Surface Transglutaminase by Membreane-type Metalloproteinase Regulates Cancer Cell Adhesion and Locomotion
  Periodical: Journal of Biological Chemistry
  Author(s): Belkin AM, Ajimov SS, Zaritskaya LS, Ratnikov BI, Deryugina EI, and Strongin AY
  Yr: 2001 Vol: 276 Nbr: Pgs: 18415-18422
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Mutation Analysis of Membreane Type-1 matrix Metalloproteinase (MT-1-MMP)
  Periodical: Journal of Biological Chemistry
  Author(s): Rozanov DV, Deryugina EI, Ratnikov BI, Monsov EZ, Marchenko GN, Quigley JP, Strongin AY
  Yr: 2001 Vol: 276 Nbr: Pgs: 25705-25714
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Functional activation of integrin avb3 in tumor cells expressing membrane-type 1 matrix metalloproteinase
  Periodical: International Journal of Cancer
  Author(s): Deryugina EI, Bourdon MA, Jungwirth K, Smith JW, and Strongin AY
  Yr: 2000 Vol: 86 Nbr: Pgs: 15-23
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Determination of Matrix Metalloproteinase Activity Using Biotinylated Gelatin
  Periodical: Analytical Biochemistry
  Author(s): Ratnikov B, Deryugina E, Leng J, Marchenko G, Dembrow D, anf Strongin A
  Yr: 2000 Vol: 286 Nbr: Pgs: 149-155
  Associated Grant: Spatial Control of Matrix Proteolysis in Breast Cancer
 
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2
  Periodical: Cancer Research
  Author(s): Deryugina EI, Bourdon MA, Reisfeld RA, and Strongin A
  Yr: 1998 Vol: 58 Nbr: 16 Pgs: 3743-3750
  Associated Grant: How are Collagenses Involved in Breast Cancer Metastasis?
 
Activation of MMP-2 modulates tumor cell migration and invasion
  Periodical: American Association for Cancer Research
  Author(s): Deryugina E, Luo G, Reisfeld R, Bourdon M, and Strongin A
  Yr: 1997 Vol: 38 Nbr: Pgs:
  Associated Grant: How are Collagenses Involved in Breast Cancer Metastasis?
 
Matrix metalloproteinase-2 activation modulates glioma cell migration
  Periodical: Journal of Cell Science
  Author(s): Deryugina EI, Bourdon MA, Luo G-X, Reisfeld RA, and Strongin A
  Yr: 1997 Vol: 110 Nbr: Pgs: 2473-82
  Associated Grant: How are Collagenses Involved in Breast Cancer Metastasis?
 
Tumor cell invasion trough matrigel is regulated by activated matrix metalloproteinase-2
  Periodical: Anticancer Research
  Author(s): Deryugina EI, Luo G-X, Reisfeld RA, Bourdon MA, and Strongin A
  Yr: 1997 Vol: 17 Nbr: 5A Pgs: 3201-10
  Associated Grant: How are Collagenses Involved in Breast Cancer Metastasis?