Scripps Research Institute

  Award Total: $11,855,306 # of Awards: 61 Home Page:

Investigators

  Daniel Bachovchin , A.B.- Gary Bokoch , Ph.D.- Ta-Hsiang Chao , Ph.D.- Kyle Chiang , Ph.D.- Justin Cisar , Ph.D.- Benjamin Cravatt , Ph.D.- Benjamin Cravatt , Ph.D.- Benjamin Cravatt , Ph.D.- Henrik Ditzel , M.D., Ph.D- Melissa Dix , B.S.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Brunhilde Felding , Ph.D.- Joel Gottesfeld , Ph.D.- Masaaki Hayashi , M.D., Ph.D.- Janis Jackson , M.D.- Janis Jackson , M.D.- Nadim Jessani , B.S.- Arul Joseph , Ph.D.- Richard Klemke , Ph.D.- Ulla Knaus , Ph.D.- Ulla Knaus , Ph.D.- Ulla Knaus , Ph.D.- Susanne Koch , Ph.D.- Anastasia Kralli , Ph.D.- Cary Hsing Chao Lai , Ph.D.- Yi Hsing Lin , Ph.D.- Ewa Lis , Ph.D.- Yongsheng Liu , Ph.D.- Qiang Liu , Ph.D.- Mihaela Lorger , Ph.D.- Beatriz Maroto , Ph.D.- Ichiro Maruyama , Ph.D.- Sherry Niessen , M.S.- Robert Ochs , Ph.D.- Randolph Piotrowicz , Ph.D.- Vito Quaranta , M.D.- Vito Quaranta , M.D.- Floyd Romesberg , Ph.D.- David Rose , D.V.M., Ph.D.- Wolfram Ruf , M.D.- Sanjay Adrian Saldanha , Ph.D.- Kevin Sato , Ph.D.- Florence Schaffner , Ph.D.- Jennifer Scorah , Ph.D.- Karin Staflin , Ph.D- Konstantin Stoletov , Ph.D.- Heimo Strohmaier , Ph.D.- Deborah Sweet , Ph.D.- Peter Vogt , Ph.D.- Xiaofei Wang , Ph.D.- Aaron Wright , Ph.D.- Xiaohua Wu , Ph.D.- Xiaohua Wu , Ph.D.- John Yates , M.D., Ph.D.-

Grants

Title[sort] Cycle Award[sort]
A new targeted therapy for breast cancer 2017 (Cycle 23) $290,250
 Investigator(s): Xiaohua Wu, Ph.D. 23IB-0020
Host Hypoxia to Treat Breast Cancer Brain Metastasis 2012 (Cycle 18) $284,250
 Investigator(s): Brunhilde Felding, Ph.D. 18IB-0022
Combating Breast Cancer with the Wellderly Immune Repertoire 2011 (Cycle 17) $473,750
 Investigator(s): Brunhilde Felding, Ph.D. 17NB-0058
Pharmacological Modulation of PP2A Activity in Breast Cancer 2010 (Cycle 16) $29,366
 Investigator(s): Daniel Bachovchin, A.B. 16GB-0062
A Chemical Strategy for Target Discovery in Breast Cancer 2010 (Cycle 16) $0
 Investigator(s): Justin Cisar, Ph.D. 16FB-0072
Inhibiting Mutation to Prevent and Treat Breast Cancer 2010 (Cycle 16) $63,021
 Investigator(s): Floyd Romesberg, Ph.D. 16IB-0037
Targeting Brain Metastasis with a Cell-based Approach 2010 (Cycle 16) $284,354
 Investigator(s): Brunhilde Felding, Ph.D. 16IB-0030
Inhibiting Breast Cancer Brain Metastasis with Cilengitide 2010 (Cycle 16) $284,435
 Investigator(s): Brunhilde Felding, Ph.D. 16IB-0052
P32: New Functional Target in Breast Cancer Brain Metastasis 2009 (Cycle 15) $71,577
 Investigator(s): Karin Staflin, Ph.D 15FB-0104
Substrate Profiling of Breast Cancer Related Proteases 2009 (Cycle 15) $76,000
 Investigator(s): Melissa Dix, B.S. 15GB-0017
Targeting DNA Repair Function of Breast Cancer Stem Cells 2009 (Cycle 15) $284,660
 Investigator(s): Xiaohua Wu, Ph.D. 15IB-0051
Combating Breast Cancer with the Wellderly Immune Repertoire 2009 (Cycle 15) $284,718
 Investigator(s): Brunhilde Felding, Ph.D. 15IB-0050
Inhibition of TF Signaling as a Novel Breast Cancer Therapy 2008 (Cycle 14) $284,250
 Investigator(s): Wolfram Ruf, M.D. 14IB-0031
Targeting Tissue Factor in Breast Cancer 2007 (Cycle 13) $89,600
 Investigator(s): Florence Schaffner, Ph.D. 13FB-0125
Neural Stem Cell Therapy for Breast Cancer Brain Metastases 2007 (Cycle 13) $419,400
 Investigator(s): Brunhilde Felding, Ph.D. 13NB-0180
Profiling Drug Metabolism (P450) Proteins in Breast Cancer 2006 (Cycle 12) $105,147
 Investigator(s): Aaron Wright, Ph.D. 12FB-0027
The Role of Serine and Metallo-Hydrolases in Breast Cancer 2006 (Cycle 12) $72,275
 Investigator(s): Sherry Niessen, M.S. 12GB-0026
The Role of Estrogen-Related Receptors in Breast Cancer 2006 (Cycle 12) $278,106
 Investigator(s): Anastasia Kralli, Ph.D. 12IB-0010
Inhibition of Brain Metastases in Breast Cancer 2006 (Cycle 12) $464,750
 Investigator(s): Brunhilde Felding, Ph.D. 12NB-0176
Neural Stem Cell Therapy for Breast Cancer Brain Metastases 2006 (Cycle 12) $302,085
 Investigator(s): Brunhilde Felding, Ph.D. 12IB-0122
The Role of Chk1 in Breast Cancer DNA Damage Repair 2006 (Cycle 12) $80,740
 Investigator(s): Jennifer Scorah, Ph.D. 12FB-0068
Inhibition of Brain Metastases in Breast Cancer 2005 (Cycle 11) $278,850
 Investigator(s): Brunhilde Felding, Ph.D. 11IB-0077
cAMP Antagonists of Protein Kinase as Breast Cancer Drugs 2005 (Cycle 11) $48,253
 Investigator(s): Sanjay Adrian Saldanha, Ph.D. 11FB-0080
Integrated Proteomic and Metabolic Analysis of Breast Cancer 2005 (Cycle 11) $59,121
 Investigator(s): Kyle Chiang, Ph.D. 11GB-0078
Imaging RhoC-induced Breast Cancer Invasion and Angiogenesis 2005 (Cycle 11) $15,725
 Investigator(s): Konstantin Stoletov, Ph.D. 11FB-0088
Defining Mutagenesis Pathways in Breast Cancer Evolution 2005 (Cycle 11) $67,520
 Investigator(s): Ewa Lis, Ph.D. 11GB-0004
Profiling Enzyme Activities in Human Breast Cancer 2004 (Cycle 10) $464,906
 Investigator(s): Benjamin Cravatt, Ph.D. 10EB-0086
Stem Cells in Breast Cancer Metastasis 2004 (Cycle 10) $621,289
 Investigator(s): John Yates, M.D., Ph.D. 10YB-0202
Stem Cells in Breast Cancer Metastasis 2004 (Cycle 10) $621,289
 Investigator(s): Brunhilde Felding, Ph.D. 10YB-0202
Activity Based Profiling of Breast Cancer Xenografts 2003 (Cycle IX) $30,000
 Investigator(s): Nadim Jessani, B.S. 9GB-0065
Inhibitors of Myc: Novel Drugs for Breast Cancer 2003 (Cycle IX) $277,887
 Investigator(s): Peter Vogt, Ph.D. 9WB-0022
Profiling Enzyme Activities in Models of Human Breast Cancer 2002 (Cycle VIII) $369,508
 Investigator(s): Benjamin Cravatt, Ph.D. 8WB-0016
Role of Pak Kinase in Breast Cancer Cell Cycle Progression 2002 (Cycle VIII) $86,400
 Investigator(s): Beatriz Maroto, Ph.D. 8FB-0026
Method to Profile Active Metalloproteases in Breast Cancer 2002 (Cycle VIII) $85,576
 Investigator(s): Arul Joseph, Ph.D. 8FB-0015
MMP-Directed Synthesis of Invasive Breast Cancer Blockers 2002 (Cycle VIII) $135,298
 Investigator(s): Vito Quaranta, M.D. 8IB-0037
The Role of SGK in Breast Cancer Proliferation 2001 (Cycle VII) $85,212
 Investigator(s): Masaaki Hayashi, M.D., Ph.D. 7FB-0028
Lasp-1 Signaling in Breast Carcinoma Cell Invasion/Migration 2001 (Cycle VII) $85,508
 Investigator(s): Yi Hsing Lin, Ph.D. 7FB-0117
Cell Growth Control of Breast Epithelial Cells 2000 (Cycle VI) $265,950
 Investigator(s): Ulla Knaus, Ph.D. 6JB-0063
The Role of the BMK1-MEKK3 Pathway in Breast Cancer 2000 (Cycle VI) $64,152
 Investigator(s): Ta-Hsiang Chao, Ph.D. 6FB-0027
Profiling Serine Protease Activities in Breast Cancer 2000 (Cycle VI) $265,950
 Investigator(s): Benjamin Cravatt, Ph.D. 6JB-0091
Identifying Breast Cancer Targets for Protease Inhibitors 2000 (Cycle VI) $42,120
 Investigator(s): Yongsheng Liu, Ph.D. 6FB-0066
Novel Mechanisms of ErbB-2-Mediated Breast Cancer Metastasis 2000 (Cycle VI) $257,006
 Investigator(s): Richard Klemke, Ph.D. 6KB-0046
Breast Cancer Cell Binding to the Endothelium 1999 (Cycle V) $326,892
 Investigator(s): Brunhilde Felding, Ph.D. 5JB-0143
Proteolysis of Cyclin E in Normal and Malignant Breast Cells 1999 (Cycle V) $31,582
 Investigator(s): Heimo Strohmaier, Ph.D. 5FB-0171
Mechanism of Radiosensitivity in Breast Cancer Cells 1999 (Cycle V) $37,200
 Investigator(s): Xiaofei Wang, Ph.D. 5FB-0169
Specificity of Ras Signaling in Breast Cancer 1999 (Cycle V) $236,706
 Investigator(s): Janis Jackson, M.D. 5JB-0139
The Role of a Newly Discovered Neuregulin in Breast Cancer 1998 (Cycle IV) $87,472
 Investigator(s): Cary Hsing Chao Lai, Ph.D. 4IB-0055
Targets of B Cell Infiltrate in Medullary Breast Cancer 1998 (Cycle IV) $279,890
 Investigator(s): Henrik Ditzel, M.D., Ph.D 4JB-0019
Regulation of Breast Epithelial Cell Motility by Proteases 1998 (Cycle IV) $464,030
 Investigator(s): Vito Quaranta, M.D. 4PB-0162
Analysis of Rac Mutations in Breast Cancer 1997 (Cycle III) $87,413
 Investigator(s): Janis Jackson, M.D. 3IB-0073
Autoantibodies in Breast Cancer 1997 (Cycle III) $130,130
 Investigator(s): Robert Ochs, Ph.D. 3IB-0083
Growth Factor Receptor Activation in Breast Cancer 1997 (Cycle III) $267,291
 Investigator(s): Ichiro Maruyama, Ph.D. 3IB-0108
The Role of PAK2 in Breast Cancer Cell Death 1997 (Cycle III) $529,149
 Investigator(s): Gary Bokoch, Ph.D. 3PB-0062
Inhibitors of the Breast Cancer Her-2/neu Gene 1997 (Cycle III) $342,796
 Investigator(s): Joel Gottesfeld, Ph.D. 3CB-0107
Disruption of Cyclin E/Cell Cycle In Breast Cancer Cells 1997 (Cycle III) $75,600
 Investigator(s): Kevin Sato, Ph.D. 3FB-0084
Integrin Receptor Activation in Breast Cancer 1997 (Cycle III) $71,564
 Investigator(s): David Rose, D.V.M., Ph.D. 3FB-0164
Novel Ways to Control the Growth of Mammary Epithelial Cells 1996 (Cycle II) $35,256
 Investigator(s): Susanne Koch, Ph.D. 2FB-0090
Zinc Finger proteins as therapeutic agents for breast 1996 (Cycle II) $43,440
 Investigator(s): Qiang Liu, Ph.D. 2FB-0138
Abnormal Regulation in Breast Cancer Development/Metastasis 1996 (Cycle II) $516,413
 Investigator(s): Ulla Knaus, Ph.D. 2RB-0229
Regulatory Mechanisms for Growth & Motility in Breast Cancer 1995 (Cycle I) $82,900
 Investigator(s): Ulla Knaus, Ph.D. 1IB-0491
HSP27 Regulation of Breast Tumor Blood Vessel Growth 1995 (Cycle I) $75,570
 Investigator(s): Randolph Piotrowicz, Ph.D. 1FB-0367
Changes in Transport into the Nucleus in Breast Cancer 1995 (Cycle I) $5,047
 Investigator(s): Deborah Sweet, Ph.D. 1FB-0489