The Burnham Institute for Medical Research

  Award Total: $18,453,617 # of Awards: 80 Home Page:

Investigators

  Robert Abraham , Ph.D.- Anissa Agadir , Ph.D.- Beatrice Bailly-Maitre , Ph.D.- Helene Baribault , Ph.D.- Helene Baribault , Ph.D.- Barbara Blouw , Ph.D.- Kelly Boatright , B.S.- Klara Briknarova , Ph.D.- Nathalie Bruey-Sedano , Ph.D.- Jason Bush , - Hee Kwang Choi , Ph.D.- Marcia Dawson , Ph.D.- Sonia del Rincon , Ph.D.- Kathryn Ely , Ph.D.- Kathryn Ely , Ph.D.- Kathryn Ely , Ph.D.- Steven Frisch , Ph.D.- Stefan Grotegut , Ph.D.- Elizabeth Hindmarsh , Ph.D.- Shi Huang , Ph.D.- Shi Huang , Ph.D.- Sharon James , Ph.D.- Yuehai Ke , Ph.D.- Youngsoo Kim , Ph.D.- Lynn Knowles , Ph.D.- Terumi Kohwi-Shigematsu , Ph.D.- Hervé Le Calvez , Ph.D.- Sug Hyung Lee , M.D., Ph.D.- Emme Lin , Ph.D.- Yi Liu , Ph.D.- Sergei Malkhosyan , Ph.D.- Sergei Malkhosyan , Ph.D.- Francesca Marassi , Ph.D.- Shu-ichi Matsuzawa , Ph.D.- Jose Millan , Ph.D.- Sonoko Narisawa , Ph.D.- Christina Niemeyer , Ph.D.- Kazuya Okada , M.D., Ph.D.- Robert Oshima , Ph.D.- Robert Oshima , Ph.D.- Robert Oshima , Ph.D.- Robert Oshima , Ph.D.- Elena Pasquale , Ph.D.- Elena Pasquale , Ph.D.- Renata Pasqualini , Ph.D.- Maurizo Pellecchia , Ph.D.- Manuel Perucho , Ph.D.- Lorena Puto , M.S.- Nicholas Rampino , Ph.D.- John Reed , M.D., Ph.D.- John Reed , M.D., Ph.D.- John Reed , M.D., Ph.D.- John Reed , M.D., Ph.D.- Marko Rehn , Ph.D.- Wanda Reynolds , Ph.D.- Adam Richardson , Ph.D.- Erkki Ruoslahti , M.D., Ph.D.- Gaurav Sharma , Ph.D.- Chung-Wai Shiau , Ph.D.- Jeffrey Smith , Ph.D.- Jeffrey Smith , Ph.D.- Jeffrey Smith , Ph.D.- Jeffrey Smith , Ph.D.- Evan Snyder , M.D., Ph.D.- Charles Spruck , Ph.D.- Charles Spruck , Ph.D.- Alex Strongin , Ph.D.- YingQing Sun , Ph.D.- Alexey Terskikh , Ph.D.- Kristiina Vuori , M.D., Ph.D.- Kristiina Vuori , M.D., Ph.D.- Kristiina Vuori , M.D., Ph.D.- Kristiina Vuori , M.D., Ph.D.- Kristiina Vuori , M.D., Ph.D.- Dieter Wolf , M.D.- Fumiichiro Yamamoto , Ph.D.- Chen Yang , Ph.D.- Juan Zapata , Ph.D.- Karin Zeh , Ph.D.- Xiao-Kun Zhang , Ph.D.- Xiao-Kun Zhang , Ph.D.- Xiao-Kun Zhang , Ph.D.- Xiao-Kun Zhang , Ph.D.-

Grants

Title[sort] Cycle Award[sort]
Novel compound to target breast cancer stem cells 2017 (Cycle 23) $292,500
 Investigator(s): Dieter Wolf, M.D. 23IB-0019
Exploiting Senescence for Breast Cancer Prevention and Treat 2015 (Cycle 21) $292,500
 Investigator(s): Charles Spruck, Ph.D. 21IB-0113
Sulindac-derived compounds for breast cancer therapy 2014 (Cycle 20) $292,498
 Investigator(s): Xiao-Kun Zhang, Ph.D. 20IB-0138
Myeloperoxidase Mediated Protection in Breast Cancer 2010 (Cycle 16) $286,500
 Investigator(s): Wanda Reynolds, Ph.D. 16IB-0111
Finding BRCA1 Ubiquitinated Substrates in Breast Cancer 2009 (Cycle 15) $191,000
 Investigator(s): Charles Spruck, Ph.D. 15IB-0130
Proline Metabolism in Metastatic Breast Cancer 2009 (Cycle 15) $284,895
 Investigator(s): Adam Richardson, Ph.D. 15IB-0095
Global Analysis of Protein Ubiquitination in Breast Cancer 2008 (Cycle 14) $89,558
 Investigator(s): Stefan Grotegut, Ph.D. 14FB-0114A
Nanotherapy for Breast Cancer Targeting Tumor Macrophages 2008 (Cycle 14) $90,000
 Investigator(s): Gaurav Sharma, Ph.D. 14FB-0107
Maternal Embryonic Leucine Zipper Kinase in Mammary Tumors 2008 (Cycle 14) $286,500
 Investigator(s): Robert Oshima, Ph.D. 14IB-0082
Mechanisms of Daxx-Mediated Apoptosis in Breast Cancer 2007 (Cycle 13) $38,000
 Investigator(s): Lorena Puto, M.S. 13GB-0056
Nur77-derived Peptides as a Novel Breast Cancer Therapy 2006 (Cycle 12) $286,108
 Investigator(s): Xiao-Kun Zhang, Ph.D. 12IB-0168
Chemical Inhibitors of Hsp70 for Breast Cancer 2006 (Cycle 12) $103,232
 Investigator(s): Chung-Wai Shiau, Ph.D. 12FB-0098
A Candidate Marker of Mammary Tumor Initiating Cells 2006 (Cycle 12) $284,262
 Investigator(s): Alexey Terskikh, Ph.D. 12IB-0079
A New Marker for Mammary Epithelial Stem Cells? 2006 (Cycle 12) $188,827
 Investigator(s): Robert Oshima, Ph.D. 12IB-0106
Modeling, Targeting Acetyl-CoA Metabolism in Breast Cancer 2006 (Cycle 12) $90,000
 Investigator(s): Chen Yang, Ph.D. 12FB-0100
The Role of Podosomes in Breast Cancer Metastasis 2006 (Cycle 12) $134,618
 Investigator(s): Barbara Blouw, Ph.D. 12FB-0076
Breast Cancer Studies in a 3-D Cell Culture System 2005 (Cycle 11) $188,602
 Investigator(s): Kristiina Vuori, M.D., Ph.D. 11IB-0132
Proteomic Profiling of Adhesive Structures in Breast Cancer 2004 (Cycle 10) $90,000
 Investigator(s): Jason Bush, 10FB-0115
Role of BI-1 Protein in Breast Cancer Apoptosis 2004 (Cycle 10) $87,424
 Investigator(s): Beatrice Bailly-Maitre, Ph.D. 10FB-0090
Stem Cells in Breast Cancer Metastasis 2004 (Cycle 10) $313,559
 Investigator(s): Evan Snyder, M.D., Ph.D. 10YB-1202
Apogossypol Derivatives for Breast Cancer Therapy 2004 (Cycle 10) $285,764
 Investigator(s): Maurizo Pellecchia, Ph.D. 10WB-0194
Maspin: Breast Cancer Suppression through Enzyme Inhibition? 2004 (Cycle 10) $196,115
 Investigator(s): Jeffrey Smith, Ph.D. 10WB-0083
Overcoming Tamoxifen-resistance in Breast Cancer 2003 (Cycle IX) $281,370
 Investigator(s): Kristiina Vuori, M.D., Ph.D. 9WB-0055
Dissection of Signaling Events in the Mammary Gland in Vivo 2003 (Cycle IX) $86,400
 Investigator(s): Yuehai Ke, Ph.D. 9FB-0170
Cell-Killing Effect of Orphan Receptor TR3 in Breast Cancer 2002 (Cycle VIII) $84,643
 Investigator(s): Nathalie Bruey-Sedano, Ph.D. 8FB-0089
Cloning of the X Chromosome's Putative Tumor Suppressor Gene 2002 (Cycle VIII) $284,375
 Investigator(s): Sergei Malkhosyan, Ph.D. 8WB-0086
Steroid Receptor Coactivators in Mammary Gland Development 2002 (Cycle VIII) $377,450
 Investigator(s): Shi Huang, Ph.D. 8WB-0092
Structure and Function of the Bax Apoptosis Regulator 2002 (Cycle VIII) $285,141
 Investigator(s): Francesca Marassi, Ph.D. 8WB-0110
Rac/STAT5 Signaling 2002 (Cycle VIII) $79,824
 Investigator(s): Hee Kwang Choi, Ph.D. 8FB-0139
Fatty Acid Synthase and Breast Cancer 2002 (Cycle VIII) $86,400
 Investigator(s): Lynn Knowles, Ph.D. 8FB-0107
PPAR Modulators as Apoptosis Sensitizers for Breast Cancer 2002 (Cycle VIII) $456,924
 Investigator(s): John Reed, M.D., Ph.D. 8WB-0079
A Novel Anti-estrogen Resistance Mechanism in Breast Cancer 2002 (Cycle VIII) $143,250
 Investigator(s): Kathryn Ely, Ph.D. 8IB-0187
Novel Retinoids with Enhanced Anti-Breast Tumor Efficacy 2002 (Cycle VIII) $378,972
 Investigator(s): Marcia Dawson, Ph.D. 8WB-0197
TR3-based Peptides for Apoptosis in Breast Cancer 2002 (Cycle VIII) $380,825
 Investigator(s): Xiao-Kun Zhang, Ph.D. 8WB-0179
Caspase-mediated Apoptosis Mechanisms in Breast Cancer Cells 2002 (Cycle VIII) $60,000
 Investigator(s): Kelly Boatright, B.S. 8GB-0137
Molecular Study of BAG Domains: A New Motif in Breast Cancer 2001 (Cycle VII) $49,869
 Investigator(s): Klara Briknarova, Ph.D. 7FB-0084
Blood Vessel Markers in Breast Cancer 2001 (Cycle VII) $378,655
 Investigator(s): Erkki Ruoslahti, M.D., Ph.D. 7WB-0033
SBP-1: A Novel Survivin Binding Protein in Breast Cancer 2001 (Cycle VII) $32,050
 Investigator(s): Kazuya Okada, M.D., Ph.D. 7FB-0052
Overcoming Drug Resistance in Breast Cancer 2001 (Cycle VII) $378,529
 Investigator(s): Kristiina Vuori, M.D., Ph.D. 7WB-0008
Protein Factor PPARg & Vitamin A Compounds in Breast Cancer 2001 (Cycle VII) $85,218
 Investigator(s): Sharon James, Ph.D. 7FB-0062
P132Cas and Antiestrogen Resistance of Breast Cancer 2001 (Cycle VII) $42,660
 Investigator(s): Marko Rehn, Ph.D. 7FB-0092
Targeting the EphB4 Receptor to Inhibit Breast Tumor Growth 2001 (Cycle VII) $184,576
 Investigator(s): Elena Pasquale, Ph.D. 7WB-0090
Suppressor Genes of Breast Cancer 2000 (Cycle VI) $195,000
 Investigator(s): Shi Huang, Ph.D. 6JB-0028
Cell Adhesion and Drug Resistance in Breast Cancer 2000 (Cycle VI) $190,773
 Investigator(s): Kristiina Vuori, M.D., Ph.D. 6JB-0017
Analysis of a New Human Caspase in Breast Cancer 2000 (Cycle VI) $51,527
 Investigator(s): Sug Hyung Lee, M.D., Ph.D. 6FB-0082
Analysis of Angiogenic Pathways in Metastatic Breast Cancer 2000 (Cycle VI) $86,400
 Investigator(s): Elizabeth Hindmarsh, Ph.D. 6FB-0037
A Vascular Restriction of Mammary Tumor Progression 2000 (Cycle VI) $384,466
 Investigator(s): Robert Oshima, Ph.D. 6JB-0073
The Shp-2 Tyrosine Phosphatase in Breast Tumor Migration 1999 (Cycle V) $75,600
 Investigator(s): YingQing Sun, Ph.D. 5FB-0087
Molecular Structure of BAG-1:a New Protein in Breast Cancer 1999 (Cycle V) $291,778
 Investigator(s): Kathryn Ely, Ph.D. 5JB-0065
How Does Endostatin Inhibit Breast Cancer Angiogenesis? 1999 (Cycle V) $292,535
 Investigator(s): Kristiina Vuori, M.D., Ph.D. 5JB-0020
Role of the EphB4 Receptor Tyrosine Kinase in Breast Cancer 1999 (Cycle V) $389,758
 Investigator(s): Elena Pasquale, Ph.D. 5JB-0086
Protease Fingerprinting to Diagnose Breast Cancer 1999 (Cycle V) $285,405
 Investigator(s): Jeffrey Smith, Ph.D. 5JB-0033
Spatial Control of Matrix Proteolysis in Breast Cancer 1999 (Cycle V) $340,383
 Investigator(s): Alex Strongin, Ph.D. 5JB-0094A
COX-2 and Apoptosis Regulation in Breast Cancer 1999 (Cycle V) $75,596
 Investigator(s): Youngsoo Kim, Ph.D. 5FB-0170
Cell Adhesion Signaling Defects in Breast Cancer 1998 (Cycle IV) $26,841
 Investigator(s): Karin Zeh, Ph.D. 4FB-0018
Siah-family Genes: Effectors of p53 in Breast Cancer 1998 (Cycle IV) $74,866
 Investigator(s): Shu-ichi Matsuzawa, Ph.D. 4FB-0103
Role of Rb Protein and Cell Cycle Defects in Breast Cancer 1998 (Cycle IV) $283,376
 Investigator(s): Kathryn Ely, Ph.D. 4JB-0001
Role of Gamma-catenin in a Breast Cancer Mouse Model 1998 (Cycle IV) $290,363
 Investigator(s): John Reed, M.D., Ph.D. 4JB-0061
Alteration of Developmental Genes in Breast Cancer 1998 (Cycle IV) $292,500
 Investigator(s): Fumiichiro Yamamoto, Ph.D. 4JB-0144
Understanding Breast Cancer Cell Metastasis to Bone 1998 (Cycle IV) $436,722
 Investigator(s): Sonoko Narisawa, Ph.D. 4KB-0106
Reprogramming Breast Cancer Epithelial Cells 1997 (Cycle III) $97,500
 Investigator(s): Steven Frisch, Ph.D. 3IB-0081
Molecular Karyotyping of Breast Cancer by DNA Fingerprinting 1997 (Cycle III) $290,550
 Investigator(s): Sergei Malkhosyan, Ph.D. 3IB-0130
Identifying Novel Breast Cancer Tumor Suppressor Genes 1997 (Cycle III) $97,500
 Investigator(s): Manuel Perucho, Ph.D. 3IB-0170
Breast Cancer Chemoprevention by Retinoids 1997 (Cycle III) $967,300
 Investigator(s): Xiao-Kun Zhang, Ph.D. 3PB-0018
Genetic Repair of Oxidative Damage: Effect of Estrogen 1997 (Cycle III) $606,017
 Investigator(s): Nicholas Rampino, Ph.D. 3PB-0176
Superfibronectin: A Novel Anti-Breast Cancer Agent 1997 (Cycle III) $389,026
 Investigator(s): Renata Pasqualini, Ph.D. 3CB-0131
Targeting T Cells to Breast Cancer 1997 (Cycle III) $388,050
 Investigator(s): Jeffrey Smith, Ph.D. 3CB-0249
The Role of Meltrin-a in Breast Cancer-Associated Bone Loss 1997 (Cycle III) $75,600
 Investigator(s): Hervé Le Calvez, Ph.D. 3FB-0025
Integrin Activation in the Metastasis of Breast Cancer 1997 (Cycle III) $264
 Investigator(s): Emme Lin, Ph.D. 3FB-0085
TRAF-regulated Signal Transduction in Breast Cancer 1997 (Cycle III) $75,600
 Investigator(s): Juan Zapata, Ph.D. 3FB-0093
Anti-breast cancer activity of vitamin A derivatives 1996 (Cycle II) $76,126
 Investigator(s): Anissa Agadir, Ph.D. 2FB-0085
Why do 70% of Breast Cancers Metastasize to Bone? 1996 (Cycle II) $97,407
 Investigator(s): Jose Millan, Ph.D. 2IB-0151
Oncogene Regulation in Mammary Cancer 1996 (Cycle II) $616,191
 Investigator(s): Robert Oshima, Ph.D. 2RB-0109
Mouse model for the loss of Bax expression in breast cancer 1996 (Cycle II) $385,198
 Investigator(s): Helene Baribault, Ph.D. 2RB-0148
Immune responses to breast cancers: function of TRAF protein 1996 (Cycle II) $284,581
 Investigator(s): John Reed, M.D., Ph.D. 2RB-0215
Prevention of Breast Cancer by Blocking Integrin Function 1995 (Cycle I) $545,057
 Investigator(s): Jeffrey Smith, Ph.D. 1RB-0020
Bax gene expression in breast cancer 1995 (Cycle I) $559,057
 Investigator(s): John Reed, M.D., Ph.D. 1RB-0093
The Role of MAR-Binding Protein in Breast Cancer 1995 (Cycle I) $223,201
 Investigator(s): Terumi Kohwi-Shigematsu, Ph.D. 1RB-0381
Cripto-A Breast Cancer Marker? 1995 (Cycle I) $75,600
 Investigator(s): Christina Niemeyer, Ph.D. 1FB-0064
Prevention of Breast Cancer Tumor Growth by Retinoic Acid 1995 (Cycle I) $10,310
 Investigator(s): Yi Liu, Ph.D. 1FB-0309